Características clínicas y tomográficas de pacientes con enfermedad cerebrovascular isquémica / Clinical and tomographic characteristics of patients with ischemic cerebrovascular disease

Introducción: El método clínico por sí solo no es definitivo para diagnosticar una enfermedad cerebrovascular, por lo que es importante el uso de medios de diagnóstico imagenológicos como la tomografía axial computarizada, que permite investigar los aspectos morfológicos y funcionales del cerebro. Objetivo: Describir las características clínicas y tomográficas de pacientes con infarto cerebral. Métodos: Se efectuó un estudio descriptivo y transversal de 269 pacientes con infarto cerebral, atendidos en el Hospital Provincial Docente Clinicoquirúrgico Saturnino Lora Torres de Santiago de Cuba, desde enero hasta diciembre de 2019. Resultados: Predominaron el sexo masculino (54,6 %), el grupo etario de 70-79 años, las afectaciones motoras (76,5 %), la alteración de la conciencia (51,3 %) y el trastorno del lenguaje (50,5 %). En 38 pacientes los resultados de la tomografía fueron negativos antes de las 24 horas de evolución y 64,0 % se consideraron mejorados con secuelas. Conclusiones: La tomografía antes de las 24 horas demuestra una baja positividad y los hallazgos evolucionan con el tiempo, aunque es posible reconocer varios signos precoces de ictus agudo en menos de 4-6 horas.

Introduction: The clinical method by itself is not definitive to diagnose a cerebrovascular disease, reason why the use of imaging diagnostic means, as the computerized axial tomography is important, as it allows to investigate the morphological and functional aspects of the brain. Objective: To describe the clinical and tomographic characteristics of patients with complete stroke. Methods: A descriptive and cross-sectional study of 269 patients with complete stroke, assisted in Saturnino Lora Torres Teaching Clinical Surgical Provincial Hospital was carried out in Santiago de Cuba, from January to December, 2019. Results: There was a prevalence of the male sex (54.6 %), 70-79 age group, motor disorders (76.5 %), alteration of the conscience (51.3 %) and language disorder (50.5 %). In 38 patients the results of the tomography were negative before the 24 hours of clinical course and 64.0 % were better with aftereffects of the disease. Conclusions: Tomography before the 24 hours demonstrates a low positivity and findings have a favorable clinical course as time goes by, although it is possible to recognize several early signs of acute ictus in less than 4-6 hours.

Clinical Application of Detection of Plasma vWF:Ag and S100B in Ischemic Cerebral Apoplexy Disease / 现代检验医学杂志

Objective To explore the clinical application value of S100B and vWF:Ag levels in ischemic cerebral apoplexy disease.Methods The plasma and clinical data from 85 cases of patients with ischemic cerebral apoplexy were collected,extracted 38 cases of volunteer blood plasma from a random sample of the general population and quantitative detected S100B levels by ELISA method,using Sysmex CA-7000 automatic blood coagulation instrument to detect plasma vWF:Ag levels.The carotid artery diameter and intima-media thickness of all the participants were detected by GELOGIC9 color doppler ultrasonic diagnostic instrument.Results The levels of plasma vWF:Ag in the CS group,the NCS (％) group and the control group were 176.8±56.3,128.9±37.6 and 93.7±30.1,which of plasma S100B (μg/L) were 2.8±1.3,1.9±0.9 and 1.3 ±0.7.Stroke patients could be divided into CS group and NCS group,compared with control group,observed the changes and the relationship of ischemic stroke disease for plasma S100B and vWF:Ag levels.The levels of plasma vWF:Ag and called S100B in the two case groups were increased compared with those in controls,the differences had statistical significance (F=125.9,89.3,P＜0.01).In CS and NCS group,vWF:Ag and S100B were comparative differences and statistically significant (F=125.9,89.3,P＜0.01),the levels of the two markers in the CS group were higher than in replication group.In CS group,the plasma levels of vWF:Ag and S100B were positively correlated (r=0.836,P＜0.01).In CS group,plasma levels of vWF:Ag were associated with carotid artery diameter and intima-media thicknes (r=-0.853,0.923,P＜0.01 and r=-0.783,0.823,P＜0.01),which of S100B did so (r=-0.820,0.833,P＜0.01).Conclution Detection of the levels of vWF:Ag and S100B can predict the degree of danger of ischemic cerebral apoplexy disease and estimate the development of the disease.